There are more than 56,000 North Carolinians incarcerated in local jails, state and federal prisons, and juvenile facilities across the state, and another 68,000 are on parole or probation in the community. The experience of incarceration is associated with higher allcause and cancer-specific mortality rates, making it an important to consider as a social determinant of health. Andrea Knittel, MD, PhD will introduce the epidemiology of cancer in prisons and jails, describe the massive cancer health disparities that are created and exacerbated by the criminal legal system, and inspire action to improve cancer care for patients impacted by the criminal legal system.