Strengthening Representation in Clinical Research: Approaches to Increase Enrollment of Underrepresented Populations

Course Information

In this course, Carrie Lee, MD, MPH and Marjory Charlot, MD, MPH, MSc present on the national professional organizations’ (e.g., ASCO, ACCC, etc.) best practices to support enrollment of populations historically underrepresented in clinical research.

They share NCI clinical trial enrollment expectations for UNC Lineberger, a comprehensive cancer center, and strategies to increase awareness of catchment area demographics and enrollment demographics. They talk about the collaboration with the UNC Lineberger Clinical Trials Office and the Office of Community Outreach and Engagement that led to research partnerships with UNC Network Community-based oncology practices. They discuss a novel clinical trial design methodology, hybrid decentralized trials, to facilitate clinical trial enrollment closer to home and how clinical trial Navigation along with community engagement can support clinical trial enrollment.

Learning Objectives

  • Describe best practices for enrolling underrepresented populations in clinical research.
  • Explain how comparison of clinical trial enrollment demographics with the population demographics of North Carolina can highlight opportunities to support enrollment of underrepresented groups and guide interventions.
  • Discuss approaches that support clinical trial enrollment through community partnerships, novel trial design and navigation resources.

 

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Please contact us with any questions at [email protected] or (919) 445–1000.

Disclaimer

The views expressed herein are those of the presenter, they do not necessarily reflect the views of the contracted organization, department, School of Medicine, nor the University of North Carolina at Chapel Hill.

 

Course summary
Available credit: 
  • 1.00 Participation
Course opens: 
06/08/2026
Course expires: 
06/07/2028
Logo for course series, Oncology Clinical Trials: a UNC Lineberger CRTEC course series 

Oncology Clinical Trials Series
Developed by Claire Dees, MD, ScM

The Oncology Clinical Trials series, developed by Claire Dees, MD, ScM, provides an introduction to clinical research in oncology, with a focus on the design and conduct of clinical trials. Topics include trial design, implementation, regulatory and ethical considerations, data management, and common challenges in oncology research.

The series also introduces complementary areas such as biomarkers, correlative studies, and other approaches that support therapeutic trials, along with considerations for career development in clinical research.

This series is designed for fellows, faculty, and oncology advanced practice providers (APPs) across cancer-related disciplines, including medical, hematologic, gynecologic, urologic, head and neck, pediatric, surgical, and radiation oncology.

Photo of Marjory Charlot, MD, MPH, MSc 

Marjory Charlot, MD, MPH, MSc

Associate Professor of Medicine
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

 

Photo of Carrie Lee, MD, mPH 

Carrie B. Lee, MD, MPH

Professor of Medicine
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Available Credit

  • 1.00 Participation
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