The Genitourinary Cancers Symposium co-sponsored by the American Society of Clinical Oncology (ASCO), American Society for Radiation Oncology (ASTRO), and Society of Urologic Oncology (SUO) provides some of the latest findings in genitourinary cancers (including prostate, bladder, kidney and testicular cancers). This lecture will highlight some of the cutting-edge research findings presented at the 2018 meeting.