Oral chemotherapy is becoming increasingly common in treatment of various malignancies. Although oral oncolytics are extremely beneficial for patients, they also present unique challenges for patients and providers alike. Implementing oral chemotherapy often requires a multidisciplinary approach. This lecture discusses several considerations for oral chemotherapy such as prescribing, patient education, adherence, medication access, cost and insurance authorization, monitoring, supportive care, and more. We will walk through a patient case to highlight practical suggestions for successful implementation of oral chemotherapy for patients.

Jose Gaston Guillem, MD, MPH, MBA, will describe how at UNC Medical Center a team of experts carefully reviews each individual patient during a Weekly GI Tumor Board and collaboratively develop a treatment plan which defines the specific timing and sequence of care for each patient.

Siddharth Sheth, DO, MPH, will provide a brief overview of clinical factors relevant to head and neck cancers and basic management. Themain focus will be the current use of technologies that aid with the diagnosis, treatment selection, and monitoring of patientswith head and neck cancers. This includes next generation sequencing assays for DNA sequencing, RNA sequencing, andcirculating tumor DNA. The goal of the presentation is for providers to be comfortable with ordering and basic interpretation ofthese tests.