This lecture is an interactive presentation and discussion to consider barriers to cancer clinical trial enrollment in North Carolina and potential approaches to address this. Topics will include the importance of patient and provider engagement, education and resources for identifying research opportunities and available trials, barriers and mitigation strategies to address population disparities in trial enrollment, and other issues. This session aims to provide information and strategies on participant recruitment, allowing individual study teams and/or clinicians from across the state to determine how research best fits into their individual models and how to present research participation as an option to all patients.